Nose-to-Brain Drug Delivery and Device Selection

October 1st 2025 - 15:00 (BST) / 10:00 (ET)

Nose-to-Brain Drug Delivery and Device Selection

October 1st 2025 - 15:00 (BST) / 10:00 (ET)

Addressed Challenges

  • Learn how formulation and device alignment can help to overcome and improve drug deposition in the olfactory region.

What You Will Learn

  • Understanding of barriers to successful brain/CNS delivery: Blood-brain barrier.
  • The benefits and challenges of Nose to Brain (N2B) Delivery.
  • Delivery Targets and Transport Mechanisms for Nose to Brain (N2B) Delivery.
  • Developing nasal dosage forms.
  • Liquid v Dry Powder and Formulation Considerations.
  • Device Considerations for Nose to Brain (N2B) delivery.
  • Practical insights into device testing methods including AINI

Dr. Richard Johnson

Chief Scientific Officer & Founder, Upperton Pharma Solutions

Dr Richard Johnson is the Founding Director and Chief Scientific Officer at Upperton Pharma Solutions, a UK-based Contract, Development and Manufacturing Organisation (CDMO) and graduated from Warwick University with a PhD Biochemistry. In 1994 he was part of a management buy-out team that founded Andaris Ltd, a research and development company exploiting the use of spray drying technology in the fields of diagnostic imaging and drug delivery. In 1999, Dr Johnson founded Upperton and has overseen significant growth and expansion over the past 25 years, specialising in spray drying and nasal drug development.
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Lara Penn

Senior Development Scientist II, Upperton Pharma Solutions

Lara Penn is a Senior Development Scientist II at Upperton Pharma Solutions in Nottingham. She holds a BSc in Pharmaceutical Chemistry from the University of Leicester. With over five years of experience, Lara has progressed from Quality Control Scientist to senior roles in formulation and project development. She specialises in analytical testing, method validation, and formulation development of oral solid dosage forms. Lara applies a science-led approach to support efficient development and manufacturing under GMP. She is skilled in HPLC, UV-Vis, FTIR, dissolution testing, and preparing technical documentation and SOPs.
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